Centronuclear myopathy " "(CNM, HMLR) ""in Great Dane and Labrador Retriever

Centronuclear myopathy


Centronuclear Myopathy (cnm) in Labrador Retrievers, formerly known as hereditary Myopathy in Labrador Retrievers (HMLR), was described in the 1970ies for the first time. CNM as a disease causes dysplasia of the dog's muscles. Therefore, affected dogs lack tendon reflexes and gain less weight than puppys of the same age (4 weeks). Obvious symptoms of HMLR first occur at weeks 12 to 20 and include general amyosthenia, aberrant bearing, awkward gait and trouble with ingestion. Affected animals exhibit low stamina and collapse when exposed to coldness. Stress causes amyotrophia, that affects head muscles at times. The same disease appears in Great Danes.


Great Dane, Labrador Retriever

Trait of inheritance


Test duration

3-5 days after arrival of the sample in the lab


The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.


Please contact our molecular biology team for further questions.

Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com


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