X-linked severe combined immunodeficiency " "(X-SCID) ""in Basset and Welsh Corgi

X-linked severe combined Immunodeficiency (X-SCID)


The X-linked severe combined Immunodeficiency (X-SCID) causes serious defects in cellular and humoral immunity. Affected dogs suffer from developmental disorder, increased responsiveness for viral and bacterial pathogens and degeneration of peripheral lymph nodes. The dogs die at the age of four month.
The source of the disease founds on a gene mutation in the interleukin-2-receptor region. For Bassets a deletion of four bases could be found, while Welsh Corgis posses an addition of one base in the gene. These mutations avert the formation of a functional receptor which normally binds to interleukin-2 and thereby causes the cells to proliferate.


Basset and Welsh Corgi

Trait of inheritance


Test duration

1-2 weeks after arrival of the sample in the lab


The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.


Please contact our molecular biology team for further questions.

Steubenstraße 4
D-97688 Bad Kissingen

Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com


 back to genetic diseases

 back to list for breeds

*) Partnerlaboratory
We are member:
Join us on