Exercise induced collapse " "(EIC) ""for breed see info

Exercise induced collapse (EIC)

Disease

EIC (exercise-induced collapse) is a recently recognised neuromuscular disorder of increasing significance in Labrador Retrievers, especially those dogs used for hunting and field trials. Recent research at the University of Minnesota has identified the gene responsible for the condition known as (EIC). A mutation in the canine dynamin 1 (DNM1) gene is very likely to be fundamentally responsible for EIC.
Due to Licensing agreements LABOKLIN can exclusively offer the EIC DNA test in Europe.
The syndrome of Exercise Induced Collapse (EIC) is manifested by muscle weakness, incoordination and life-threatening collapse after intense exercise. Five to fifteen minutes of strenuous exercise causes dogs suffering from this condition to develop a „wobbly“ gait, which soon progresses to nonpainful, flaccid paraparesis and a loss of control of the rear limbs. The episode may progress to all four limbs. Collapse episodes usually last for 5-10 minutes, and after 30 minutes there is often complete recovery, but episodes are occasionally fatal. The rectal temperature of dogs during an episode typically reaches 41.7°C (from a resting temperature of 39°C).

Breed

Boykin Spaniel, Chesapeake Bay Retrievers, Clumber Spaniel, Curly Coated Retrievers, Labrador Retrievers, Old English Sheepdog, Pembroke Welsh Corgi and Wire-hair Pointer

Trait of inheritance

autosomal-recessive

Test duration

3-5 days after arrival of the sample in the lab

Material

The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.

Questiones?

Please contact our molecular biology team for further questions.

LABOKLIN GmbH und Co.KG
Steubenstraße 4
D-97688 Bad Kissingen

Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com

Links

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