Hyperkalemic Periodic Paralysis (HYPP)

Disease

Hyperkalaemic Periodic Paralysis has been reported in Quarter Horses (Offsprings of the stallion “Impressive”) and horses with Quarterhorse blood (Apaloosas and Paints). The disease is characterized by intermittent episodes of muscular fasciculations, weakness, myotonia, or involuntary recumbency. HYPP is the result of a genetic mutation in the sodium channel gene of skeletal muscles. It is inherited as an autosomal dominant trait. That means that a heterozygous carrier of the defect gene shows the same symptoms than a horse with both allels affected.

Breed

Quarter Horse, Paint Horse, Appaloosa and related breed

Trait of inheritance

autosomal-dominant

Test duration

3-5 days after arrival of the sample in the lab

Material

The DNA test is performed out of EDTA blood or or 20-30 hair roots from mane or tail. Test kits can be ordered free of charge. (order-form). If hair is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.

Questiones?

Please contact our molecular biology team for further questions.

LABOKLIN GmbH und Co.KG
Steubenstraße 4
D-97688 Bad Kissingen

Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com

Links

 back to genetic diseases

 back to list for breed


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