Polycystic kidney disease (PKD)

PKD causes the formation of hepatic and renal cysts as well as of fluid-filled renal cysts, often... more
Disease
Feline polycystic kidney disease is an inherited disease in Persian and Persian related cats. PKD causes the formation of hepatic and renal cysts as well as of fluid-filled renal cysts, often leading to renal failure. Cystic kidneys can sporadically occur in any population of cats, but early onset and bilateral presentation is a hallmark to the hereditary form. The kidney cysts for PKD are present early, generally before 12 months, but renal failure generally occurs at a later time, thus it is considered a late onset renal disease. The presence of cystic kidneys can be determined by 6 to 8 months of age by ultrasonic techniques and affection diagnosis is generally certain by one to two years. Average age for renal dysfunction, not failure, is 7 years for cats with PKD. Thus, with out imaging techniques, cats would go undiagnosed for PKD for many years. Clinical signs are non specific but common to cats experiencing renal dysfunction, including depression, anorexia, reduced appetite, polyuria, polydypsia, and weight loss.
Breed
Birman (Sacred cat of Burma), British Longhair, British Shorthair (BSH), Chartreux, Exotic Shorthair, Persian, Ragdoll, Russian Blue, Scottish Fold Longhair, Scottish Fold Shorthair, Selkirk Rex Longhair, Selkirk Rex Shorthair, Turkish Angora
Heredity
autosomal dominant
Test duration
3 - 5 days
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