(American Eskimo Dog, American Hairless Terrier, Australian Cattle Dog, Chinese Crested, Danish... more
autosomal recessive; In most cases heterozygous carriers are healthy. However, it is estimated that about 2 20% of the carriers will develop PLL.
HeredityDogs affected from PLL have painful glaucomas and blindness due to a dislocation of the lens due to a breakdown or disintegration of the zonula fibres. PLL can be inherited or acquired. First clinical signs of the inherited form of PLL are detectable at the very young age of 20 months. A complete lens luxation typically occurs at the age of 3 to 8 years.
TaqMan SNP Assay