Acatalasemia

Disease
Acatalasemia is characterized by the deficiency of the enzyme catalase which is important for cellular defence in oxidative stress. Affected dogs suffer from ulcers and tissue death in the oral cavity. The disease has only been recognised in a laboratory colony of Beagle dogs. The acatalasemia phenotype caught particular interest as an animal model of a human condition called Takahara’s disease.
Breed
Beagle
Heredity
autosomal recessive
Test duration
1-2 weeks after arrival of the sample in the lab
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