C3 deficiency (C3)
The third component (C3) of the complement system plays an important role in the immune response... more
Disease
The third component (C3) of the complement system plays an important role in the immune response to microbes like bacteria, fungi or parasites. The causative mutation prohibits the formation of functional C3 units and the chain of defence mechanisms is broken. Affected dogs exhibit higher susceptibility to bacterial infections. Glomerulonephritis, caused by C3-deficiency dependant cell death in the complement system, is often diagnosed for those dogs.
Heredity
autosomal recessive
Test duration
1-2 weeks after arrival of the sample in the lab
