(Bull Terrier, Miniature Bull Terrier) more
autosomal recessive with incomplete penetrance
Bull Terrier, Miniature Bull Terrier
HeredityLaryngeal paralysis means that the dog is not able to abduct the arytenoid cartilages during inspiration which could result in partial airway obstruction and consequent respiratory distress. Clinical signs of laryngeal paralysis include decreasing exercise tolerance, progressive laryngeal stridor, voice impairment, episodes of breathing difficulties and collapsing. In the breeds Bull Terrier and Miniature Bull Terrier, a variant could be identified to be a major genetic risk factor for an early onset from of laryngeal paralysis. Homozygosity for this variant is associated with a 23-fold increased risk for laryngeal paralysis.