The Progressive Retinal Atrophy(PRA) leads to a degeneration of the retina and results in... more
Progressive retinal atrophy (PRA) is a leading hereditary cause of blindness in pedigree dogs as is its counterpart retinitis pigmentosa (RP) in humans. PRA shows genetic heterogeneity, as does RP, with several distinct forms already recognized and several more remaining to be investigated. One can distinguish between late onset forms of PRA and early onset (whelp-age) dysplastic changes. The clinical and ophthalmologic signs of both forms are similar. Affected dogs suffer from bilateral Mydriasis, the reflection of the Tapetum lucidum is increased and the retinal vascular network appears atrophic.
Bullmastiff, Cardigan Welsh Corgi, Chinese Crested Dog, Irish Red and White Setter, Irish Setter, Mastiff, Pomeranian, Sloughi