Protein losing nephropathy (PLN)

The Risk assessment for PLN is possible due to genetic testing. Hereditary PLN starts often with... more
Disease
Hereditary PLN in Soft-Coated Wheaten Terrier starts with a hidden proteinuria in midlife. The disease can proceed mildly and stay steady for years. In some cases severe complications like kidney failure or thromboses occur. Risk assessment for PLN is possible due to genetic testing, now. Nevertheless, starting point and development of symptoms vary hugely and are supposed to depend on enviromental factors and modifying genes. Additionally, aquired forms of PLN disease can not be detected by the genetic test.
Breed
Heredity
Heterozygous dogs possess medium risk, homozygous affected dogs possess high risk to develop symptoms of the disease.
Test duration
3-5 days after arrival of the sample in the lab
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