Leonberger polyneuropathy (LPN1)

The type 1 neuropathy (LPN1) in Leonberger starts at the age of 2-4 year and shows a severe... more
Disease
The type 1 neuropathy (LPN1) in Leonberger starts at the age of 2-4 year and shows a severe progression. The symptoms of this polyneuropathy include wobbly gait and paralysis especially from the backhand. Affected dogs are not able to stand up in the final stage of the disease. Breathing noises, strange barking voice and difficulties in swallowing are other typical symptoms. The causative mutation causes around 20% of all polyneuropathy cases in the Leonberger breed. Other aetiologic mutations exist.
Breed
Leonberger
Heredity
autosomal recessive
Test duration
1-2 weeks after arrival of the sample in the lab
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