Cleft lip/palate and syndactyly (CLPS)

Affected puppies are born with cleft palate and cleft lips, as well as fusion of the middle toes,... more
Disease
Cleft Lip / Palate and Syndactyly (CLPS) describes a hereditary diseasein Nova Scotia Duck Tolling Retrievers. Two different genetic defects were found to be the cause of this disease: One mutation is located in the gene CP1, another mutation is located in the gene ADAMTS20, which is responsible for similar syptoms in humans. Early on, affected puppies develop a cleft palate, cleft lips, as well as the pathological growth along the middle toes, which is called syndactyly.
Breed
Nova Scotia Duck Tolling Retriever
Heredity
autosomal-recessive
Test duration
1-2 weeks after arrival of the sample in the lab
Join us on
Facebook!