DNA-Profiling

Webflyer: "Premium SNP DNA profile (ISAG 2020)"

Premium SNP DNA profile (ISAG 2020)

The Premium SNP DNA-profile (ISAG 2020) is your animal's genetic fingerprint. It cannot be manipulated or destroyed, remains unchanged for a lifetime and allows unambiguous identification of the individual. All DNA-profiles are stored in our DNA database, thus ensuring continuous availability. The Premium SNP DNA-profile (ISAG 2020) follows the recommended ISAG (International Society for Animal Genetics) guidelines from 2020 by analyzing 230 SNPs (single nucleotide polymorphisms) and enables international comparability between laboratories. Each SNP marker describes a specific location on the DNA. Test reliability and exclusion probabilities for parentage analysis are well over 99.99%. The Premium SNP DNA profile (ISAG 2020) also has the potential to solve parentage cases where only one parent is available (breeds on request) and furthermore allows an analysis of the genetic diversity and the heterozygosity of a dog with breed-specific evaluation (for clubs on request).

Please note: Premium SNP DNA-profile (ISAG 2020) and Classic STR DNA profiles (ISAG 2006) are not compatible and cannot be used simultaneously within the same parentage analysis.

Species

dog

Breed

all breeds

Test duration

4-6 weeks after arrival of the sample in the lab


LABOGEN Diversity Check (diversity.labogen.com)

The consequent avoidance of inbreeding is an important feature of responsible dog breeding. The genetic diversity of a population or breed reflects the degree of inbreeding it has experienced in the past. When inbreeding is avoided for many generations, it is reflected by a high level of genetic diversity. Especially in pedigree dogs, there may be an increased risk of inbreeding, for example due to closed stud books and excessive mating of “popular sires”. This is associated with a loss of genetic diversity and inbreeding depression, i.e. the accumulation of genetic variants that are harmful and cause disease. Health effects such as reduced immune competence or low reproductive success can also be signs of inbreeding depression.
The LABOGEN Diversity Check shows the genetic relationship of dogs of the same breed as your animal(s) and allows the identification of genetically unrelated individuals. In breeds with very low genetic diversity, inbreeding may also be present among unrelated animals due to the genetic uniformity within the breed. The LABOGEN Diversity Check helps to find suitable breeding partners and to avoid inbreeding.
In addition, the LABOGEN Diversity Check always shows the most up-to-date information on the distribution of heterozygosity in the breed or club population. This is another feature that can help to maintain a healthy population. The heterozygosity value indicates the genetic variability of the individual dog. Each individual inherits half of the genes from its mother and half from its father. The less genetically related the parents are, the higher may be the heterozygosity of the offspring.
With the LABOGEN Diversity Check, we offer support for maintaining and increasing genetic diversity in the long term and promote the health of future generations in a sustainable way. Simply order the Premium SNP DNA profile from LABOKLIN and get free access to the LABOGEN Diversity Check for your dog.

FAQs on Genetic Variability (Heterozygosity)

What is genetic diversity and why is it important?

How is the genetic diversity calculated?

What does the genetic diversity chart of the LABOGEN Diversity Check show?

What does the heterozygosity (genetic variability) chart of the LABOGEN Diversity Check show?

How do we calculate the heterozygosity value?

How do I interpret values when I do not see a curve in the heterozygosity graph?

What does the axis label of the graph in the LABOGEN Premium SNP DNA profile mean?

How do I use the activation code on my findings? How do I register for the LABOGEN Diversity Check?

What is the difference between breed distribution and club distribution?

Which test do I need to order to have the genetic diversity or my animal’s heterozygosity tested?

Which sample material is needed?

How long does it take before I get the results?

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