Protein losing nephropathy (PLN)
Disease
Hereditary PLN in Soft-Coated Wheaten Terrier starts with a hidden proteinuria in midlife. The disease can proceed mildly and stay steady for years. In some cases severe complications like kidney failure or thromboses occur. Risk assessment for PLN is possible due to genetic testing, now. Nevertheless, starting point and development of symptoms vary hugely and are supposed to depend on enviromental factors and modifying genes. Additionally, aquired forms of PLN disease can not be detected by the genetic test.
Breed
Soft-Coated Wheaten Terrier
Trait of inheritance
Heterozygous dogs possess medium risk, homozygous affected dogs possess high risk to develop symptoms of the disease
Test duration
3-5 days after arrival of the sample in the lab
Material
The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.
Testing procedure
Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.
Questiones?
Please contact our molecular biology team for further questions.
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D-97688 Bad Kissingen
Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com
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