Atrophie progressive de la rétine (prcd-PRA) Optigen **

The Progressive Retinal Atrophy (PRA) leads to a degeneration of the retina and results in...plus
Disease
The Progressive Retinal Atrophy as an inherited form leads to a degeneration of the retina and results in blindness. The Retina which is composed of photoreceptor cells as well as nerve cells covers the back inside wall of the eye and is responsible for image formation. The photoreceptor cells can be divided into rods or cones depending on their function. The rod cells are specialised for the mesopic vision and contrast sensitivity. The con cells are responsible for color vision. The prcd-PRA causes initially a loss of function of the rod cells accompanied by night blindness. At later stages the cone cells become affected leading to a complete blindness of the dog. Age of onset of clinical symptoms is typically in early adolescence or early adulthood. However, the onset of the disease may vary among different dog breeds.
Breed
Bearded Collie, Berger anglais, Berger australien, Berger australien miniature, Berger finnois de laponie, Bichon bolonais, Bolonka Zwetna, Bouvier australien, Bouvier australien courte queue, Bouvier de l'Entlebuch, Caniche, Caniche nain, Caniche toy, Chien chinois à crête, Chien d'eau espagnol, Chien d'eau portugais, Chien d'eau romagnol, Chien d'elan norvegien, Chien d'ours de Carélie, Chien finnois de Laponie, Chihuahua, Cocker américain, Cocker spaniel anglais, Esquimau américain, Grand Spitz, Kuvasz, Labradoodle, Lapphund suédois, Markiesje, Retriever de la baie de chesapeake, Retriever de la Nouvelle-Écosse, Retriever du Labrador, Retriever Golden, Schipperke, Schnauzer geant, Spitz, Terrier australien à poil soyeux, Wäller, Yorkshire Terrier
Heredity
autosomal recessive
Test duration
4-6 weeks after arrival of the sample in the lab
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