Coat colour variation Burma and Siam (point)

Characteristic and trait of inheritance

The Siamese pattern is reponsible for a phenotype representing a mild form of albinism. This temperature-sensitive mutation produces normal colour pigment only at the cooler extremities of the body, causing a ”mask” of the face as well as darkened paws and tail. The Siamese pattern is also called mask factor or point, since normal pigmentation occurs only at the cooler points of the body.
The Burmese pattern, the mildest form of albinism, is characterized by a normal pigmentation of the extremities and a slight shading of normal body colour.
Two mutations in the gene encoding the enzyme tyrosinase which is required for melanin production are responsible for these colour variants. This gene locus is called C-locus. The wild type allele C is dominant and causes full pigmentation, the Siamese cs allele is recessive and leads to the characteristic distribution of the dark colour on ears, mask, tail and legs when in the homozygous state. The Burmese pattern also follows a recessive inheritance and leads to the coat colour Burmese brown in the homozygous state, with varying degrees of black and dark brown.

Breed

All breed

Test duration

1-2 weeks after arrival of the sample in the lab

Material

The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.

Questiones?

Please contact our molecular biology team for further questions.

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