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CDPA autosomal dominant; CDDY semi dominant (leg length) or dominant (IVDD risk)
Тип наследованияIn many dog breeds, Chondrodystrophy (CDDY) and/or Chondrodysplasia (CDPA) cause a short leg phenotype. However, CDDY is associated with a high risk of premature degeneration of the invertebral discs (Hansens type I intervertebral disc disease, IVDD).
CDPA is inherited in an autosomal dominant manner and especially known in short-legged breeds.
Regarding the length of the legs, CDDY is inherited as semi dominant trait. This means that heterozygous dogs have shorter legs than dogs tested as free, while affected dogs show a more drastic reduction of the leg length than heterozygous dogs. The risk for IVDD is inherited in a dominant manner, therefore one copy of the variation is sufficient to predispose dogs to IVDD.