Hereditary Deafness (EOAD)

In the breeds Rottweiler, Beauceron and Rhodesian Ridgeback, different breed specific genetic... more
Заболевание
In the breed Rottweiler, a genetic variant of the LOXHD1 gene causes an early-onset hearing loss. At the moment, it is still unclear if the puppies are born with deafness or if they are born with hearing impairment which progresses to deafness until the age of a few weeks. The LOXHD1 gene is suspected to be involved in maintaining the function of the cochlear hair cells.

In the breed Beauceron, a genetic variant in the gene CDH23 causes congenital, non-syndromic deafness with bilateral hearing loss. Affected puppies showed a normal growth except for the deafness.

Rhodesian Ridgeback dogs suffer from an early onset adult deafness, a progressive form of hearing loss leading to deafness in the age of one to two years. This disease is caused by a deletion in the EPS8L2 gene.
Порода
босерон, родезийский риджбек, ротвейлер
Тип наследования
autosomal recessive
Длительность теста
1-2 weeks after arrival of the sample in the lab
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