Hereditary myopathy (CNM)

(German Hunting Terrier, Great Dane, Labrador Retriever) more
Заболевание
autosomal recessive
Порода
немецкий ягдтерьер, немецкий дог, лабрадор-ретривер
Тип наследования
Affected dogs of the breeds Labrador Retriever and Gret Dane lack tendon reflexes and gain less weight than puppies of the same age. Obvious symptoms first occur at weeks 12 to 20 including general amyosthenia, aberrant bearing, awkward gait and trouble with ingestion. Affected animals exhibit low stamina and collapse when exposed to coldness.

Typical symptoms of Excercise induced metabolic myopathy (EIMM) in the breed German Hunting Terrier are signs of exercise induced weakness, muscle pain, rhabdomyolysis and brownish discoloration of the urine during or after exercise. That’s the reason why affected dogs of this breed should not be used as hunting dogs since they collapse and develop tetraparesis to tetraplegia after 30 to 120 minutes of exercise.
Длительность теста
sequencing (Great Dane); FLP (Labrador Retriever); TaqMan SNP assay (German Hunting Terrier)
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