Leukoencephalopathy (LEP)

(Schnauzer) more
Заболевание
autosomal recessive
Порода
шнауцер
Тип наследования
In the breed Standard Schnauzer, several puppies with neurological signs such as dysphagia, non-ambulatory tetraparesis, hypermetric ataxia, circling, dysphoria, head tilt, strabismus, generalized tonic-clonic seizures or sudden death have been described. Through whole genome sequencing of affected dogs and comparing with dogs without any symptoms, a variant could be found to be associated with leukoencephalopathy in this breed. Due to several clinical signs, affected puppies were usually euthanized a few days after birth.
Длительность теста
sequencing
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