Neuronal ceroid lipofuscinosis (NCL)
Die Neuronale Ceroid Lipofuszinose (NCL) ist eine neurodegenerative Erkrankung aufgrund von...lisää
Disease
NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction.
The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
Breed
Australian Cattle Dog,
Australian Shepherd,
Dachshund (Dackel),
Long-Haired Dachshund,
Miniature American Shepherd,
Short-Haired Dachshund,
Wire-Haired Dachshund
Heredity
autosomal recessive
Test duration
3 - 5 days after arrival of the sample in the lap, in case of sequencing 1-2 weeks (Australian Cattle Dog, Australian Shepherd, Miniature American Shepherd)
1 2 weeks (Dachshund)
1 2 weeks (Dachshund)
