Neural tube defects result from abnormal closure or development of the neuronal tube during... altro
Neural tube defects result from abnormal closure or development of the neuronal tube during embryogenesis. In the Weimaraner breed, a mutation of the regulatory homebox gene NKX2-8, which is expressed in the developing tube, could be found to be associated with the neural tube defect, termed spinal dysraphism. The spinal dysraphism is a non-progressiv ataxia and is characterised by the following symptoms: abnormal hair streams along the back, kinked tails, scoliosis in the lumbar spinal region, paraparesis, bunny-hopping, crouched stance.
1-2 weeks after arrival of the sample in the lab