In Trapped neutrophil syndrome (TNS) affected dogs, neutrophils are produced by the bone marrow,...plus
In TNS affected dogs, neutrophils are produced by the bone marrow, but lack the ability to reach the blood stream. Therefore, affected puppies posses a weak immune system and are not able to fight pathogens effectively. The variable symptoms observed depend on the respective infection. Equally, starting point and severity of the TNS-disease vary, with most of the dogs dying before the fifth month of their live. In rare cases, dogs can live a normal life due to antibiotic- and steroid-therapies.
3-5 days after arrival of the sample in the lab