Nanisme dysharmonieux

The disease becomes evident at the age of about 2 months. Affected dogs have a shorter height and...plus
Disease
A genetic variant of the PRKG2 gene has been found to be associated with disproportionate dwarfism in the breed Dogo Argentino. The disease becomes evident at the age of about 2 months. Affected dogs have a shorter height and body length. A disproportionally large head with a pronounced vertical groove between the eyes and forelimb angular aberrations (carpus valgus) that can cause gait abnormalities are also typical symptoms of the disease.

The PRKG2 gene encodes for a protein which has a signalling role in the termination of chondrocyte proliferation and initiation of the differentiation into bone.
Breed
Dogue argentin
Heredity
autosomal recessiv
Test duration
1-2 weeks after arrival of the sample in the lab
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