Gallbladder mucoceles causes mucinous hyperplasia of the gallbladder wall and accumulation of...plus
Gallbladder mucoceles are caused by a mutation in the ABCB4 gene. This mutation leads to mucinous hyperplasia of the gallbladder wall and accumulation of mucus resulting in an extended gallbladder. Undetected gallbladder mucoceles can lead to cholecystitis and rupture of the gallbladder. Clinical signs occur in older dogs showing vomiting, anorexia, lethargie, icterus and abdominal pain.
Cairn Terrier, Chien de berger des shetland (Sheltie), Cocker américain, Cocker spaniel anglais, Spitz nain (Poméranien)
autosomal dominant with incomplete penetrance
1-2 weeks after arrival of the sample in the lab