Pituitary dwarfism
Disease
Dwarfism is a condition of abnormally small stature with additionally altered proportions in some body parts. Pituitary dwarfism in German shepherds produces perfectly proportioned but miniaturized dogs. It is caused by a gen defect, which leads to dysfunction of the pituitary gland. As a result, lower amounts of growth hormones and Thyroxine reach the blood. Hence, affected dogs stop to grow between week three to eight of their live.
These dogs posses fox-like appearance characterized by set apart ears, pointed muzzle and slight over-bite. Sometimes, they twinkle more in bright sunlight then dogs from the same litter. Untreated, dogs retain their puppy-fluff or completely loose their hair, with the exception of the feed and head region. In this case, they look much like Chinese crested dogs. Also, altered hormon-composition often leads to un- or malformed genitals.
When treated with growth hormones and Thyroxine, dogs can live a normal live.
Breed
German Shepherd, Saaloos Wolfdog, Czechoslovakian Wolfdog
Trait of inheritance
Test duration
1-2 weeks after arrival of the sample in the lab
Material
The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.
Testing procedure
Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.
Questiones?
Please contact our molecular biology team for further questions.
LABOKLIN GmbH und Co.KG
Steubenstraße 4
D-97688 Bad Kissingen
Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com
Links
*) Partnerlaboratory