Coagulation factor XII is involved in the intrinsic cascade of blood coagulation. Two different... more
Coagulation factor XII is involved in the intrinsic cascade of blood coagulation. Two different mutations have been described in the factor XII gene that trigger FXII deficiency. Homozygous affected cats have a strongly reduced FXII activity, while heterozygous affected cats only show a moderately reduced FXII activity. FXII deficiency manifests as prolonged clotting time in the partial thromboplastin time (PTT) screening test. Affected cats have not experienced abnormal bleeding.
1-2 weeks after arrival of the samples in the lab