Affected puppies die at birth or at a maximum age of 6-8 weeks. In the latter case, the puppies... more
In the breed Belgian Shepherd Dog, a genetic variant has been found to correlate with cardiomyopathy and juvenile mortality (CJM). Affected puppies die at birth or at a maximum age of 6-8 weeks. In the latter case, the puppies initially develop normally but then show unspecific symptoms like vomiting, uncoordinated movements, trembling or respiratory symptoms and die a few days after the first clinical signs, usually due to heart failure. The genetic analysis of CJM enables the selective mating of breeding dogs. Because of the autosomal recessive trait, dogs tested as carriers should not be eliminated from breeding, but mated with dogs that do not carry this variant in order to avoid affected puppies.
Belgian Shepherd Dog, Groenendael, Laekenois, Malinois, Tervueren
3-5 days after arrival of the sample in the lab (in case of sequencing 1-2 weeks)