Haemophilia A (factor VIII deficiency)

The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and... more
Disease
The underlying pathomechanism of Haemophilia A is a lack or decreased activity of factor VIII that plays a critical role in the coagulation cascade. Affected dogs present with hemorrhage that can vary from mild to severe depending on the degree of the disease. The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and joints. If the disease is severe and no precautions are taken, affected dogs can bleed to death after surgery or injuries.
Breed
Boxer, German Shepherd, Old English Sheepdog, Rhodesian Ridgeback
Heredity
X chromosomal recessive
Test duration
3-5 days after arrival of the sample in the lab (German Shepherd, Rhodesian Ridgeback); 1-2 weeks after arrival of the sample in the lab (Boxer, Old English Sheepdog)
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