Congenital idiopathic megaesophagus (CIM) affected dogs show symptoms like regurgitation of meal... more
Congenital idiopathic megaesophagus (CIM) is characterized as a gastrointestinal motility disorder preventing the normal transport of food within the stomach by reduced peristaltic activity and dilation of the esophagus. Affected dogs show regurgitation of meal and water and therefore failing to thrive. Complications as aspiration pneumonia can occur. The German shepherd breed has a high incidence of CIM due to a genetic predisposition: sex and a genetic variant raise the likelihood of CIM. Male dogs are twice likely affected than female ones. Additionally, a genetic variant is associated with the appearance of signs with the homozygous state posing the most significant risk. Additional factors influence the occurrence of CIM. The genetic test allows the increasing of the low-risk-allele by targeted breeding.
German Shepherd Dog
1-2 weeks after arrival of the sample