Progressive Retinal Atrophy (PRA4)

In the breed Lhasa Apso, a variant of the IMPG2 could be associated with PRA. The age of onset in... more
Disease
The Progressive Retinal Atrophy as an inherited form leads to a degeneration of the retina and results in blindness. The Retina which is composed of photoreceptor cells as well as nerve cells covers the back inside wall of the eye and is responsible for image formation. The photoreceptor cells can be divided into rods or cones depending on their function. The rod cells are specialised for the mesopic vision and contrast sensitivity. The con cells are responsible for color vision. In the breed Lhasa Apso, a variant of the IMPG2 could be associated with PRA. The age of onset in this breed is variable. First clinical signs could be present at the age of 2.5 years. But sometimes it takes several years until the owner will notice the symptoms of the disease.
Breed
Lhasa Apso
Heredity
autosomal recessive
Test duration
1-2 weeks after arrival of the sample in the lab
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