NCL is a neurodegenerative disease: the clinical course includes increasing levels of agitation... more
NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction. The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
American Bulldog, Border Collie, Chihuahua, Chinese Crested Dog, Dachshund (Dackel), English Setter, Golden Retriever, Gordon Setter, Italian Corso Dog, Long-Haired Dachshund, Miniature Australian Shepherd, Saluki, Short-Haired Dachshund, Tibetan Terrier, Wire-Haired Dachshund
3-5 days after arrival of the sample in the lab (American Bulldog, Border Collie, English Setter, Golden Retriever, Gordon Setter, Tibetan Terrier); 1-2 weeks (Chinese Crested Dog, Chihuahua, Dachshund, Italian Cane Corso, Saluki)