Upper Airway Syndrome (UAS)

While brachycephalic dogs are predisposed to the Brachycephalic Obstructive Airway Syndrome... more
Disease
The Norwich Terrier is considered to be a “mesocephalic” breed, which means that the linear measurement of the hard palate of Norwich Terriers revealed intermediate plate dimensions compared to the hard palate of other dog breeds. While brachycephalic dogs are predisposed to the Brachycephalic Obstructive Airway Syndrome (BOAS), the Upper Airway Syndrome (UAS) could often be observed at dogs of the breed Norwich Terrier. Respiratory effort, resulting in laboured breathing, intolerance to heat or exercise, cyanosis and collapse are typical symptoms of both syndromes (UAS and BOAS).
In the breed Norwich Terrier, a variant in the ADAMTS3 gene could be found to be associated with the UAS. Homozygous affected dogs often show an elongated soft palate protruding caudally into the epiglottis, the laryngeal cartilage is inverted into the lumen of the airway and the laryngeal saccules are everted.
Breed
Norwich Terrier
Heredity
autosomal dominant with incomplete penetrance
Test duration
1-2 weeks after arrival of the sample in the lab
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