A-locus Agouti

Characteristic and trait of inheritance

The A locus is responsible for a number of common coat patterns in the dog. Expression of the A-locus requires any combination of two ky or kbr alleles at the K locus, and at least one E or EM allele at the E locus. The Agouti gene and its variations determine the coat colours fawn / sable (Ay), wild type (aw), tan points "", and recessive black(a).
Ay analysis proves absence or presence of the mutation typically responsible for fawn or sable. In fawn / sable dogs this test shows if other agouti alleles are present but hidden (only one copy of Ay). It also demonstrates how many copies of this allele are hidden in dogs, which cannot express agouti types (KB/KB, KB/kbr, KB/ky, at the k locus and/or e/e at the E locus).
The analysis of a shows whether a black dog is black due to “recessive black,” or the more common black at the K locus. It also reveals non-black animals carrying “recessive black.” (e.g. German Shepherd Dog, Shetland Sheepdog).

Breed

All breed

Test duration

around one week after arrival of the sample in the lab

Material

The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.

Questiones?

Please contact our molecular biology team for further questions.

LABOKLIN GmbH und Co.KG
Steubenstraße 4
D-97688 Bad Kissingen

Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546
E-Mail: info@labogen.com

Links

back to genetic characteristics