Genetic blood group determination
Blood group in cat
The AB system is the major blood group system in domestic cats. The common blood types are A and B. Cats with bloodtype B have anti-A antibodies at a high titer and cats with blood type A have anti-B antibodies at a low titer. Cats with the rare AB blood type do not have anti-A or anti-B antibodies.
These natural antibodies can leed to bloodgroup incompatibility that can be lethal. First symptoms are dyspnea, vomiting and agitation.
Neonatal isoerythrolysis occurs when a female cat with blood type B is bred to an A-type male cat and the A-type kitten absorb the anti-A antibodies from the breast milk. The hemolytic disease that ensues can be lethal.
The DNA test for cat blood group factors has not been fully validated in the following breeds: Ragdoll, Turkish Angora, Bengal, Serval, Chausie and wildcats and their hybrids. In some animals, results from DNA and serological tests are not concordant.
In about 2% of the cases, results are inconclusive and status of the B blood group cannot be determined for these cats. This indicates that there are additional mutations yet to be identified.
Trait of inheritance
The genetic determination of the blood group in cats enables the genetic differentiation of the serologically determined blood group before breeding.
Blood typ A is dominat to b. With the gene test it´s possible to identify the recessive b allel which is associated with the B serotyp. Cats with two copies of the b allel have the Type B bloodgroup.
Cats with blood group A can carry the genetic information either for AA or Ab.
Approximately one week after arrival of the sample in the lab
The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.
Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.