EH-locus (sable)

Characteristic and trait of inheritance

Sable is a coat colour variant in which the expression of eumelanin is partially inhibited. The typical markings are a pale mask and a dark blanket. A mutation at the E-locus, located between E and e, is responsible for this phenotype. It is called eh.
A genetic test is only available for American and English Cocker Spaniel. The corresponding coat colour variant is called “grizzle” in Salukis and “domino” in Afghan Hounds. The mutation in these breeds is thought to be in the E-locus as well, however the genetic test is only validated for Cocker Spaniels.


American Cocker Spaniel and English Cocker Spaniel

Test duration

1-2 weeks after arrival of the sample in the lab


The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.

Testing procedure

Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer.
Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.


Please contact our molecular biology team for further questions.

Steubenstraße 4
D-97688 Bad Kissingen

Telefon: +49 (0)971 72020
Fax: +49 (0)971 68546


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